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Table 1 Parameter values used in the computer simulations. (Note that the dimension of λi, (i = 0, 1,..., N) is cm-2 s-1, but it becomes s-1 when dimensioness number densities are used).

From: A continuum mathematical model of endothelial layer maintenance and senescence

Parameter Value Description
N 50 number of generations from progenitor to senescence
D 10-8 cm2 s-1 diffusion coefficient of dead cells
k 0 0 s-1 death rate coefficient of progenitor cells
k N 0.6 × 10-7 s-1 death rate coefficient of senescent cells
k i (i = 1,..., N - 1) (kN + 1)i/N - 1 s-1 death rate coefficient of cells of age i
λ 0 0.4 × 10-4 s-1 division rate constant of progenitor cells
λ N 0 s-1 division rate constant of senescent cells
λ i (i = 1,..., N - 1) (λ0 + 1)(N-i)/N - 1 s-1 division rate constant of cells at age i
γ 10-9 - 10-8 day-1 ≈ (10-9 - 10-8) × 10-5 s-1 homing rate coefficient of progenitor cells
δ 6 × 10-7 s-1 clearance rate coefficient of dead cells