| |
Start-end
|
D%
|
E%
|
H%
|
K%
|
R%
|
D+E%
|
K+R%
|
H+K+R%
|
|
|
|---|
|
ABCC5-TMD1
|
179 – 454
|
1.1
|
4.3
|
0.7
|
5.4
|
4.3
|
5.4
|
9.7
|
10.4
|
1.7
|
1.8
|
|
ABCC5-TMD2
|
848–1147
|
3.7
|
2.3
|
2.3
|
2.7
|
5.3
|
6
|
8
|
10.3
|
1.3
|
1.7
|
|
ABCC5, both TMDs
| | | | | | | | | |
1.5
|
1.8
|
|
ABCB1-TMD1
|
52–346
|
3.7
|
5.1
|
1.4
|
4.7
|
3.4
|
8.8
|
8.1
|
9.5
|
0.9
|
1.1
|
|
ABCB1-TMD2
|
711–994
|
2.8
|
3.5
|
1.1
|
4.9
|
4.2
|
6.3
|
9.1
|
10.2
|
1.4
|
1.6
|
|
ABCB1, both TMDs
| | | | | | | | | |
1.1
|
1.4
|
- Positive-negative ratios of charged amino acids. The percentages % of aspartate (D), glutamate (E), histidine (H), lysine (K), and arginine (R), and positive-negative ratios of charged amino acids in ABCB1-TMD1, ABCB1-TMD2, ABCC5-TMD1, and ABCC5-TMD2. The positive-negative ratio of amino acids is higher in the ABCC5 TMDs (1.5, 1.8 including histidine) than in the ABCB1 TMDs (1.1, 1.4 including histidine).
