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Figure 25 | Theoretical Biology and Medical Modelling

Figure 25

From: The Proteomic Code: a molecular recognition code for proteins

Figure 25

Independence of sequence and structure of a protein and its mRNA. The amino acids in a U-shaped protein structure are encoded by complementary codons (rule PC1). The nucleic acid structure is uniform and the folding energy is -132 kcal/mol. Exactly the same amino acid sequence might be encoded by non- or only partially complementary codons, which will fundamentally alter the mRNA structure and increase the folding energy to -31 kcal/mol (less stable). The nucleic acid structures were generated by mfold and dGs were calculated by the same program.

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