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Figure 5 | Theoretical Biology and Medical Modelling

Figure 5

From: Simulating non-small cell lung cancer with a multiscale agent-based model

Figure 5

Weight of decision rules on changing cell phenotypes. Influence on changing cell migration (left panel) and proliferation (right panel) when following the corresponding rule (see Fig. 3). The dashed red line indicates rule A-mediated migrations in (a), while the dashed blue line denotes rule B-mediated proliferations in (b). Fitting curves in solid black are calculated using a standard linear least squares method. Slopes of the fitting curves are 1.40 cells/step in (a) and 0.03 cells/step in (b), respectively. Note: The drop of the dashed red line in the left panel of (a) is caused by the termination of the simulation when a cell reached the source (in this case, no further computation on remaining cells will be performed).

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