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Table 1 Symbols used in kinetic model

From: Relating a calcium indicator signal to the unperturbed calcium concentration time-course

Symbol

Name of Quantity

Units

V(t)

Membrane voltage

mV

x(t)

Free calcium concentration

Mol

y(t)

Indicator bound calcium

Mol

ymax

Total free and bound indicator

Mol

α(t)

Calcium influx

Mol/sec

γ

Pump rate

1/sec

kf

Forward binding constant

1/(Mol sec)

kb

Backward binding constant

1/sec

KD

Dissociation constant = kb/kf

Mol

Rf

dimensionless forward rate kfymax/γ

-

Rb

dimensionless backward rate kb/γ

-