Figure 7

Transient responses of HPA axis a simulated stress experiment. The same stress was given with two different initial conditions; normal steady state (low GR concentration) that would occur in a control group, and low cortisol state (high GR concentration) that would occur in a patient group. Stress was given for 0<Time<1 hr. Dash and solid lines indicate the normal and dysregulated HPA axis responses respectively and stress is indicated with shading.