Skip to main content


Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Figure 7 | Theoretical Biology and Medical Modelling

Figure 7

From: Inclusion of the glucocorticoid receptor in a hypothalamic pituitary adrenal axis model reveals bistability

Figure 7

Transient responses of HPA axis a simulated stress experiment. The same stress was given with two different initial conditions; normal steady state (low GR concentration) that would occur in a control group, and low cortisol state (high GR concentration) that would occur in a patient group. Stress was given for 0<Time<1 hr. Dash and solid lines indicate the normal and dysregulated HPA axis responses respectively and stress is indicated with shading.

Back to article page