Skip to main content
Figure 12 | Theoretical Biology and Medical Modelling

Figure 12

From: Introduction of an agent-based multi-scale modular architecture for dynamic knowledge representation of acute inflammation

Figure 12

Timecourses for "Candidate" variables in Post-ischemic Gut Lymph. Graph of the dynamics of three potential "candidates" for the yet unidentified pro-inflammatory compound seen in post-ischemic mesenteric lymph. Note that the units of the three graphs have been adjusted to show their time-courses side-by-side; the emphasis is on the patterns of the timecourses rather than the absolute values. The "cell-damage-byproduct" graph best follows the reported characteristics of post-ischemic mesenteric lymph, with the greatest rises in pro-inflammatory activity at 3 and 6 h, and persisting to 24 h. "NO" rises early enough for the pro-inflammatory effect at 3 and 6 h, but is not present at 24 h. The "Gut-leak" is delayed in its rise, and therefore cannot account for activity seen at 3 and 6 h.

Back to article page