Figure 5

Reduced models under induction by FasL. Reduced models of apoptosis under induction by FasL (receptor-mediated apoptosis; [FasL]₀ = 2 nM unless noted), with time course validations. In (a) and (c), the time courses of the full and reduced models essentially overlap. (a) HeLa cell induced by FasL. (b) Jurkat T cell induced by FasL. (c) Jurkat T* cell induced by low FasL ([FasL]₀ = 0.01 nM).