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Table 1 The MLEs of the model parameters and the QTL position derived from 200 simulation replicates assuming complete maternal imprinting. The square root of the mean square errors (RMSEs) of the MLEs are given in parentheses.

From: Functional mapping imprinted quantitative trait loci underlying developmental characteristics

   

Q M Q P

Q M q P

q M Q P

q M q P

Residual

H 2

n

Position (cM)

α 1

36.5

β 1

6.5

γ 1

0.75

α 2

33.5

β 2

5.5

γ 2

0.75

α 3

36.5

β 3

6.5

γ 3

0.75

α 4

33.5

β 4

5.5

γ 4

0.75

σ 2

ρ

0.8

0.1

200

45.31 (7.506)

36.52 (0.478)

6.50 (0.135)

0.75 (0.010)

33.74 (0.992)

5.60 (0.333)

0.75 (0.014)

36.22 (0.998)

6.38 (0.341)

0.75 (0.015)

33.47 (0.438)

5.50 (0.117)

0.75 (0.011)

0.0086 (0.001)

0.79 (0.014)

 

NI

45.54 (8.267)

36.5685 (0.515)

6.53 (0.147)

0.75 (0.010)

35.03 (1.579)

5.99 (0.504)

0.75 (0.007)

35.03 (1.554)

5.99 (0.523)

0.75 (0.007)

33.42 (0.464)

5.48 (0.115)

0.75 (0.011)

0.009 (0.001)

0.81 (0.013)

0.1

500

45.88 (3.615)

36.54 (0.305)

6.51 (0.087)

0.75 (0.006)

33.72 (0.866)

5.57 (0.285)

0.75 (0.009)

36.32 (0.832)

6.42 (0.272)

0.75 (0.009)

33.49 (0.289)

5.50 (0.071)

0.75 (0.006)

0.0089 (0.0005)

0.80 (0.008)

 

NI

46.12 (4.483)

36.59 (0.323)

6.53 (0.089)

0.75 (0.006)

34.97 (1.486)

5.97 (0.477)

0.75 (0.005)

34.97 (1.541)

5.97 (0.501)

0.75 (0.005)

33.41 (0.304)

5.48 (0.079)

0.75 (0.006)

0.009 (0.0006)

0.81 (0.01)

0.4

200

46.33 (2.671)

36.51 (0.206)

6.50 (0.057)

0.75 (0.004)

33.54 (0.352)

5.51 (0.111)

0.75 (0.004)

36.46 (0.361)

6.49 (0.112)

0.75 (0.004)

33.49 (0.186)

5.50 (0.045)

0.75 (0.004)

0.0015 (0.0003)

0.80 (0.014)

 

NI

47.63 (4.625)

36.67 (0.251)

6.56 (0.080)

0.75 (0.004)

34.96 (1.502)

5.98 (0.495)

0.75 (0.005)

34.96 (1.582)

5.98 (0.532)

0.75 (0.004)

33.38 (0.212)

5.45 (0.065)

0.75 (0.004)

0.0018 (0.0003)

0.82 (0.027)

0.4

500

46.07 (1.684)

36.48 (0.119)

6.50 (0.031)

0.75 (0.002)

33.50 (0.127)

5.50 (0.034)

0.75 (0.003)

36.49 (0.145)

6.50 (0.037)

0.75 (0.003)

33.49 (0.123)

5.50 (0.030)

0.75 (0.002)

0.0015 (0.0001)

0.80 (0.007)

 

NI

48.21 (2.644)

36.67 (0.215)

6.56 (0.072)

0.75 (0.002)

34.97 (1.487)

5.98 (0.486)

0.75 (0.002)

34.97 (1.551)

5.98 (0.526)

0.75 (0.002)

33.36 (0.182)

5.45 (0.057)

0.75 (0.003)

0.0018 (0.0003)

0.83 (0.029)

  1. The location of the simulated QTL is described by the map distances (in cM) from the first marker of the linkage group (100 cM long). The hypothesized σ2 value is 0.009 for H2 = 0.10 and 0.0015 for H2 = 0.4. The analysis results by non-imprinting model are indicated by "NI".