Figure 5From: Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determinationPrediction of tissue concentration of domperidone using the WS model (black line) in any tissue/organ included in the PBPK model. Tissue concentration measured in WT mice (black lozenge) and KO mice (black circle) after IV administration of 5 mg/kg of domperidone. BLQ = Below Limit of Quantification.Back to article page