Figure 4
From: Binding site of ABC transporter homology models confirmed by ABCB1 crystal structure
A-C : Backbone Cα-traces of ABCB1 model (A), ABCC4 model (B) and ABCC5 model (C) viewed from intracellular side. Colour coding: blue via white to red from N-terminal to C-terminal. D - F: The water-accessible surfaces of ABCB1 model (D), ABCC4 model (E) and ABCC5 model (F) viewed from intracellular side collared coded according to the electrostatic potentials 1.4 Å outside the surface; negative (-10 kcal/mol), red to positive (+10 kcal/mol), blue. G-I: Cross sections along the inner membrane layer of water-accessible surfaces of ABCB1 model (G), ABCC4 model (H) and ABCC5 model (I) viewed from intracellular side, colour coding as D-F. All illustrations are in similar view.