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Figure 2 | Theoretical Biology and Medical Modelling

Figure 2

From: Theoretical study of the Usutu virus helicase 3D structure, by means of computer-aided homology modelling

Figure 2

A: Ribbon representation of the produced Usutu virus helicase model. B: the Usutu virus helicase model superimposed with its Murray Valley Encephalitis virus helicase template (RCSB entry: 2V80). The Usutu virus helicase model is in red, whereas the Murray Valley Encephalitis virus helicase template is in green and the ssRNA substrate (coordinates obtained from 1A1V [24]) is in magenta. C: All residues surrounding the ssRNA fragment, color-coded as B. The ssRNA interacting regions are almost identical between the Usutu virus helicase model and the MVE helicase template. D: The interaction map of the per-residue ssRNA interaction pattern from Ligplot for Usutu virus helicase model (left) and the Murray Valley Encephalitis virus helicase template (right). Conserved residues that are involved in the ssRNA binding and are common between the Usutu virus helicase model and the MVE helicase template have been connected with a line.

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