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Table 1 Stimulated steady-state values for low glucose (5 mM) (see text for explanations)

From: Glucose sensing in the pancreatic beta cell: a computational systems analysis

Parameters

Simulated value

Experimental value

References

[Ca2+]c

0.09 μ M

~0.1 μ M

[49, 52]

[G3P]

2.79 μ M

  

[PYR]

8.62 μ M

  

[ATP]c/[ADP]c

4.6

~3 - 6

[7, 12, 51]

[NADH]c

0.97 μ M

  

Ψm

94.7 mV

  

[NADH]m

57.2 μ M

60 μ M

[47]

[Ca2+]m

0.242 μ M

0.25 μ M

[48]

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Theoretical Biology and Medical Modelling

ISSN: 1742-4682