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Table 3 Outcomes of competition between resident population using OxPhos and mutant cells using glycolysis.

From: Cancer proliferation and therapy: the Warburg effect and quantum metabolism

Resource Constraints

Selective Outcome

(I) Limited resources

Ox Phos [(almost always) = (a.s.)]

   Constant distribution

 

(II) Abundant resources

 

   Variable Distribution

Glycolysis (a.s.)

(III) Limited Resources

 

   Variable distribution:

 

Large population size

   Ox Phos (a.s.)

Small population size

   Ox Phos (with probability that increases with population size)

(IV) Abundant resources

 

   Constant distribution

 

Large population size

   Glycolysis (a.s.)

Small population size

   Glycolysis (with probability that increases with population size)