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Figure 2 | Theoretical Biology and Medical Modelling

Figure 2

From: Chemotherapy in conjoint aging-tumor systems: some simple models for addressing coupled aging-cancer dynamics

Figure 2

The evolution of normal cells and tumor cells during the phase of therapy. The drug is considered to be static. First row: the drug does not have any effects on normal cells, a N (1 - emu) = 0, and a T (1 - emu) = 0.01 (red), 0.05 (green), 0.1 (black). Second row: the drug kills both normal and tumor cells with more killing strength on the tumor cells. Blue represents the untreated system when a N (1 - emu) = 0 = a T (1 - emu) = 0. From there, the response of the tumor cells is considered to be constant, a T (1 - emu) = 0.1, while a variation is considered for the response of normal cells as: a N (1 - emu) = 0.01 (red), 0.05, (green), 0.1 (black). Third row: the drug kills both normal and tumor cells with more killing strength on normal cells. blue is untreated system when a N (1 - emu) = 0 = a T (1 - emu) = 0, From there, the response of the normal cells is considered to be constant, a N (1 - emu) = 0.1, while a variation is considered for the response of the normal cells as: a T (1 - emu) = 0.01 (red), 0.05, (green), 0.1 (black). The rest of the parameters are similar to the common parameter introduced in Figure [1].

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