Table 4 Steady State Values from WT to SERT KO
From: Serotonin synthesis, release and reuptake in terminals: a mathematical model
| Â | f* = 1(WT) | f= .5 | f= .2 | f= .1 | f= .05 | f= 0(SERT KO) |
|---|---|---|---|---|---|---|
trp | 20.1 | 20.9 | 21.1 | 21.1 | 21.2 | 21.3 |
c 5 - HT | 0.5 | 0.39 | 0.3 | 0.25 | 0.19 | 0.05 |
v 5 - HT | 21.5 | 19.9 | 18.1 | 17.05 | 14.67 | 6.41 |
e 5 - HT ** | .7 | 1.18 | 1.82 | 2.26 | 3.32 | 6.2 |
5 - hiaa | 5.3 | 4.12 | 3.13 | 2.7 | 1.99 | 0.63 |
V TPH | 5.57 | 4.59 | 3.86 | 3.6 | 3.32 | 3.12 |
V MAT | 21.4 | 16.7 | 10.7 | 7.09 | 5.87 | 2.56 |
V SERT | 21.1 | 16.2 | 9.93 | 6.16 | 4.5 | 0.0 |
V rem | 0.31 | 0.47 | 0.73 | 0.9 | 1.33 | 2.50 |
V catab | 5.26 | 4.12 | 3.13 | 2.7 | 1.99 | 0.63 |