From: Population genetics of cancer cell clones: possible implications of cancer stem cells
Tumour Size (cm) | Number of cells | Estimated number of generations to establish a favourable mutation in a somatic cell clone | Estimated number of generations to establish a favourable mutation in a stem cell clone |
---|---|---|---|
0.1 | 4 189 | 6 | 1 |
0.5 | 523 599 | 8 | 3 |
1.0 | 4 188 790 | 9 | 4 |
2.0 | 33 510 322 | 10 | 5 |
3.0 | 11 3097 336 | 10 | 5 |
4.0 | 268 082 573 | 10 | 6 |
5.0 | 523 598 776 | 11 | 6 |
10.0 | 4 188 790 205 | 12 | 7 |