Table 4 Effect of differing selective advantages on the rate of clonal evolution.
From: Population genetics of cancer cell clones: possible implications of cancer stem cells
Selective advantage of clone A over clone a | Number of generations needed for the relative proportion of clone A to change from 1% to 99% |
|---|---|
0.01 | 924 |
0.05 | 188 |
0.10 | 96 |
0.50 | 23 |
0.75 | 16 |
1.00 | 13 |
2.00 | 8 |
5.00 | 5 |