Figure 20

Long term Ca²⁺ stability during repetitive stimulation. Figure 20: The stimulation protocol used is a pulse train of amplitude (-40 mv to 10 mv) and frequency of 0.33 Hz.(A) Integrals of external and internal Ca²⁺ currents on stimulation with repetitive long pulses (800 ms); (B) Percentage of changes in [Ca²⁺] _myo peak magnitude and cumulative SR Ca²⁺ loss on stimulation with repetitive short pulses (100 ms); (C) Integrals of external Ca²⁺ currents with short-pulse stimulations (100 ms); (D) Integrals of internal Ca²⁺ currents with short-pulse stimulations (100 ms). This model-generated result shows similarity to data in Figure 3 and Figure 5, Negretti et al. [111].