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Table 10 Initial Conditions

From: Modeling CICR in rat ventricular myocytes: voltage clamp studies

State variable

Definition

Initial Value

P 1

Fraction of inactive dephosphorylated CaMKII in Ca2CaM bound state

5.527608 × 10-1

P 3

Fraction of active dephosphorylated CaMKII in Ca4CaM bound state

3.661260 × 10-1

P 6

Fraction of active Thr287-autophosphorylated but CaM autonomous CaMKII

1.314410 × 10-3

P 5

Fraction of active Thr287-autophosphorylated but Ca2CaM bound CaMKII

6.277911 × 10-7

P 4

Fraction of active Thr287-autophosphorylated but Ca4CaM trapped CaMKII

9.121920 × 10-8

  1. Table 10: Initial conditions used for the state vector in order to solve the linearized system of ordinary differential equations
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Theoretical Biology and Medical Modelling

ISSN: 1742-4682