Modeling CICR in rat ventricular myocytes: voltage clamp studies

Table 5 Rate constants used to model Ca/CaM binding and CaM buffering

Rate Constant	Value	Rate Constant	Value
$k_{02}^{C M}$	4.8387^‡	$k_{42 B}^{C M}$	$k_{42}^{C M}$
$k_{20}^{C M}$	10.0*	$k_{0 B o n}^{C M}$	3.5 × 10^-4‡
$k_{24}^{C M}$	3.4722^‡	$k_{0 B o f f}^{C M}$	1.4 × 10^-6‡
$k_{42}^{C M}$	500.0*	$k_{2 B o n}^{C M}$	$k_{0 B o n}^{C M}$
$k_{02 B}^{C M}$	$k_{02}^{C M}$	$k_{2 B o f}^{C M}$	$k_{0 B o f f}^{C M}$
$k_{20 B}^{C M}$	$k_{20}^{C M}$ /100	$k_{4 B o n}^{C M}$	$k_{0 B o n}^{C M}$
$k_{24 B}^{C M}$	$k_{24}^{C M}$	$k_{4 B o f f}^{C M}$	$k_{0 B o f f}^{C M}$

Table 5: Rate constants used to model Ca/CaM binding and CaM buffering. Adopted (*) or estimated (‡) from Saucerman et. al. [38].

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