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Figure 3 | Theoretical Biology and Medical Modelling

Figure 3

From: Propagation of kinetic uncertainties through a canonical topology of the TLR4 signaling network in different regions of biochemical reaction space

Figure 3

Ensemble of hypothetical dynamical trajectories. A wide spectrum of hypothetical but biologically plausible dynamical trajectories accessible to the reaction network was simulated. An ensemble encompassing 100 different trajectories accessible in widely scattered regions of biochemical reaction space were propagated from very particular initial conditions. The figure illustrates a subset of individual dynamical trajectories displayed by some key reaction species modeled (100 trajectories for each species are shown). Most of these simulated trajectories were found to be capable of displaying transient or sustained dynamical features, which have been reported to be typical dynamical behaviors emerging during crucial intracellular signaling events.

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