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Table 2 Statistics on Overall State Senstivities from Local Perturbations Experiments for the Transcriptional Output Cxcl10. Values shown were averaged over the ensemble of 10 reference parameter configurations evaluated. Mean-D (mean D Statistic); SD-D (standard deviation of D Statistic)

From: Propagation of kinetic uncertainties through a canonical topology of the TLR4 signaling network in different regions of biochemical reaction space

Parameter ΔP= 10% ΔP= 20% ΔP= 30% ΔP= 40% ΔP= 50% Mean-D SD-D
Kb 0.007726 0.005217 0.006069 0.004233 0.004070 0.005463 0.007836
n 0.005616 0.004478 0.003862 0.003824 0.003714 0.004299 0.007452
k 40f 0.002317 0.002146 0.002607 0.002518 0.002238 0.002365 0.006197
k 42f 0.003415 0.002004 0.001858 0.001902 0.001834 0.002203 0.004786
k 21cat 0.002860 0.002644 0.001749 0.001634 0.001206 0.002019 0.002098
k 16r 0.004237 0.002285 0.001129 0.000868 0.000731 0.001850 0.002971
kps 0.003663 0.002090 0.001305 0.001196 0.000839 0.001819 0.002631
k 23cat 0.003425 0.002015 0.001266 0.001124 0.000651 0.001696 0.002657
k 33r 0.003194 0.002201 0.001196 0.001030 0.000760 0.001676 0.002669
k 23f 0.003989 0.002014 0.001034 0.000723 0.000590 0.001670 0.002982
k 19r 0.002917 0.001721 0.001572 0.000947 0.000739 0.001579 0.002649
k 8 0.002686 0.001737 0.001478 0.000968 0.000540 0.001482 0.002459
k 22f 0.002733 0.001615 0.000998 0.001147 0.000826 0.001464 0.002661
k 23r 0.002807 0.001821 0.001181 0.000786 0.000697 0.001458 0.002383
k 7r 0.002639 0.001675 0.001317 0.000935 0.000648 0.001443 0.002659
k 32f 0.001537 0.002349 0.001265 0.001116 0.000824 0.001418 0.001876
k 24 0.002710 0.001463 0.001237 0.000729 0.000597 0.001347 0.002629
kas 0.001528 0.002123 0.001111 0.000830 0.000810 0.001280 0.002070
k 1r 0.001324 0.001825 0.001397 0.000960 0.000753 0.001252 0.001656
k 18r 0.001279 0.001625 0.001444 0.000881 0.000708 0.001187 0.001692