The BIS_2010 agents representing nodes in a static representation of the immune network. Each node in the immune network represents a category of immune cells that includes subtypes. Solid lines indicate two-way connections that involve a change in information recorded by both nodes upon contact. Dashed lines indicate interactions in which only one node, usually the Macrophage Agent, records information about the contact because the other node represents an agent that is dead. The agents representing leukocytes are pink or green, indicating their function in innate or adaptive immunity.