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Figure 7 | Theoretical Biology and Medical Modelling

Figure 7

From: Using an agent-based model to analyze the dynamic communication network of the immune response

Figure 7

Frequency distributions of contacts for each immune agent type at 400 ticks. The plots show the frequency distribution of the contacts as log10 of the number of nodes vs. the log10 of the number of links per node for the first 400 ticks of the simulation for the given agent type and outcome. 7A) BCell Agent's win contacts, 752 points, Spearman r = -0.9418, p < 0.0001; 7I) BCell Agent's loss contacts, 792 points, Spearman r = -0.7857, p < 0.0001; 7B) TCell Agent's win contacts, 661 points, Spearman r = -0.8675, p < 0.0001; 7J) TCell Agent's loss contacts, 281 points, Spearman r = -0.7679, p < 0.0001; 7C) Dendritic Agent's win contacts, 1843 points, Spearman r = -0.8482, p < 0.0001; 7K) Dendritic Agent's loss contacts, 2266 points, Spearman r = -0.8936, p < 0.0001; 7D) CTL Agent's win contacts, 187 points, Spearman r = -0.9439, p < 0.0001; 7L) CTL Agent's loss contacts, 269 points, Spearman r = -0.9509, p < 0.0001; 7E) Macrophage Agent's win contacts, 277 points, Spearman r = -0.9586, p < 0.0001; 7M) Macrophage Agent's loss contacts, 317 points, Spearman r = -0.9771, p < 0.0001; 7F) Natural Killer Agent's win contacts, 16 points, Spearman r = -0.6676, p = 0.0047, the correlation coefficient r = -0.106 is not significant; 7N) Natural Killer Agent's loss contacts, 16 points, Spearman r = -0.6794, p = 0.0038, the correlation coefficient r = -0.140 is not significant; 7G, 7O) Granulocyte Agent's contacts, with only 2 points, the correlation cannot be determined; 7H) Combined immune agent's win contacts, 1912 points, Spearman r = -0.8954, p < 0.0001; 7P) Combined immune agent's loss contacts, 2274 points, Spearman r = -0.9088, p < 0.0001.

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