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Figure 8 | Theoretical Biology and Medical Modelling

Figure 8

From: Using an agent-based model to analyze the dynamic communication network of the immune response

Figure 8

Frequency distributions of contacts for each immune agent type at 1000 ticks. The plots show the frequency distribution of the contacts as log10 of the number of nodes vs. the log10 of the number of links per node for all 1000 ticks of the simulation for the given agent type and outcome. 8A) BCell Agent's win contacts, 1732 points, Spearman r = -0.7197, p < 0.0001; 8I) BCell Agent's loss contacts, 2353 points, Spearman r = -0.6487, p < 0.0001; 8B) TCell Agent's win contacts, 756 points, Spearman r = -0.8636, p < 0.0001; 8J) TCell Agent's loss contacts, 368 points, Spearman r = -0.8192, p < 0.0001; 8C) Dendritic Agent's win contacts, 3444 points, Spearman r = -0.7669, p < 0.0001; 8K) Dendritic Agent's loss contacts, 17218 points, Spearman r = -0.9074, p < 0.0001; 8D) CTL Agent's win contacts, 216 points, Spearman r = -0.9488, p < 0.0001; 8L) CTL Agent's loss contacts, 580 points, Spearman r = -0.9257, p < 0.0001; 8E) Macrophage Agent's win contacts, 310 points, Spearman r = -0.9630, p < 0.0001; 8M) Macrophage Agent's loss contacts, 470 points, Spearman r = -0.9896, p < 0.0001; 8F) Natural Killer Agent's win contacts, 16 points, Spearman r = -0.6853, p = 0.0034, the correlation coefficient r = -0.1945 is not significant; 8N) Natural Killer Agent's loss contacts, 16 points, Spearman r = -0.6912, p = 0.0030, the correlation coefficient r = -0.4899 is not significant; 8G, 8O) Granulocyte Agent's contacts, too few point for correlation to be determined; 8H) Combined immune agent's win contacts, 3603 points, Spearman r = -0.8657, p < 0.0001; 8P) Combined immune agent's loss contacts, 17250 points, Spearman r = -0.9097, p < 0.0001.

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