Figure 2

Similarity measures (weakly cooperative Adair-Klotz model, h = 3). Generated in the same way as Figure 1, but with a higher value for the Hill coefficient (h = 3). The parameters of the Hill model were optimized in the same way as for Figure 1, resulting in α = 0.5s^-1, β = 0.083s^-1. Increase in the Hill coefficient makes the discrepancy larger since there are more intermediate states that can be populated. The similarity in the distributions shape increases for large times.