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Table 1 Binding motifs found from fREDUCE for keloid versus normal fibroblasts under serum starvation condition (P > 1

From: Insights gained from the reverse engineering of gene networks in keloid fibroblasts

Normalization

Parameters

Binding Motif

P-value

Correlation

MAS 5

(unfiltered)

Length 7

(0 IUPAC)

CCGGCC

5.31

0.0558

  

GCCGAC

1.99

0.0432

 

Length 7

(1 IUPAC)

CGCBGA

5.30

0.0605

  

MCGGAA

1.42

0.0469

RMA

(unfiltered)

Length 7

(0 IUPAC)

GCCGAC

3.35

0.0487

  

CACATAT

2.56

-0.0480

 

Length 7

(1 IUPAC)

GBCGAC

3.56

0.0549

  

CACATAT

2.02

-0.0470

MAS 5

(filtered)

Length 7

(0 IUPAC)

CGCCGA

2.86

0.0616

 

Length 7

(1 IUPAC)

CGCCBA

3.65

0.0726

RMA

(filtered)

Length 7

(0 IUPAC)

CGCCGA

2.58

0.0561

  

TATACAC

1.95

-0.0560

 

Length 7

(1 IUPAC)

CACAKAT

2.33

-0.0649

  

CGCCGA

2.03

0.0548

  1. Note: P-values are shown as -log10 values.
  2. IUPAC characters M = C/A; Y = C/T; K = T/G; B = C/T/G, V = A/C/G