Table 2 Possible gene targets and TFs found from the TRANSFAC database for top binding motifs from Table 1
From: Insights gained from the reverse engineering of gene networks in keloid fibroblasts
Binding Motif | Possible gene targets | Possible TFs |
|---|---|---|
CCGGCC | MC2R (melanocortin 2 receptor) | SF-1 |
| Â | MT1G (metallothionein 1G) | - |
| Â | EPO (erythropoietin) | Tf-LF1 and Tf-LF2 |
| Â | SURF1 and SURF2 (surfeit 1 and 2) | YY1 |
GCCGAC | ATF2 (activating transcription factor 2) | SP1 |
CGCCGA | c-myb | MZF-1 |
CACATAT | - | - |