Figure 4

Glucose-induced insulin secretion in perifused human islets in response to stepwise glucose increments. Glucose concentration in the perifusing solution increases from 1 mM (G1) to 30 mM (G30) as indicated. Values calculated with the present model (red line, — ) are shown superimposed on the same time-scale over data determined experimentally (blue disks, ●; redrawn from [40]).