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Figure 11 | Theoretical Biology and Medical Modelling

Figure 11

From: A nucleotide binding rectification Brownian ratchet model for translocation of Y-family DNA polymerases

Figure 11

Interaction potentials between a Y-family DNA Pol and a DNA substrate with a mismatched base pair at the n th site shown in top of (a). For clarity, the mismatched base is drawn in pink. (a) V1(x) represents the potential of the binding site S1 interacting with the DNA substrate, while V2(x) represents the potential of the binding site S2 interacting with the DNA substrate. (b) Schematic diagrams of the position of the Pol along the DNA substrate, with blue dots representing the active site.

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