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Table 5 Results of the fit to the Hodgkin data for the different dose-response models for sarcoma induction.

From: Site-specific dose-response relationships for cancer induction from the combined Japanese A-bomb and Hodgkin cohorts for doses relevant to radiotherapy

Site

Low repopulation R = 0.1

(Eq.10)

Intermediate repopulation R = 0.5

(Eq.10)

Full tissue recovery R = 1

(Eq.11)

 

β †

α *

CV

β †

α *

CV

β †

α *

CV

Bone

1.70

0.019

2.1E-4

0.20

0.067

1.1E-3

0.10

0.078

4.3E-3

Soft tissue

3.30

0.040

1.9E-6

0.60

0.060

1.7E-4

0.35

0.093

5.8E-4

  1. The fitted variables β and α are listed for each organ and for three different values for R (0.1, 0.5 and 1.0). In addition the coefficient of variation (CV) is given.
  2. * in Gy-1
  3. † in (10,000 PY Gy)-1
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Theoretical Biology and Medical Modelling

ISSN: 1742-4682