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Figure 16 | Theoretical Biology and Medical Modelling

Figure 16

From: Agent-based dynamic knowledge representation of Pseudomonas aeruginosa virulence activation in the stressed gut: Towards characterizing host-pathogen interactions in gut-derived sepsis

Figure 16

GMABM response to phosphate depletion alone. Selected frames from the model interface taken at 6, 12, 24 and 48 hrs of simulated time during simulation of phosphate depletion in the integrated GMABM. Pseudomonas agents are red pentagons and intact tight junctions are seen as the purple background, with black background indicating severe barrier disruption. Phosphate depletion alone yielded moderate to severe barrier disruption after 48 hours. This response was more severe than expected given prior experimental referent data.

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