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Table 2 The effect of the Ginkgo biloba extracts on oxidative stress parameters associated with CIS-treatment in testicular tissues of rats

From: Neural network assessment of herbal protection against chemotherapeutic-induced reproductive toxicity

Parameters

N

GB

CIS

CIS + L

CIS + M

CIS + H

MDA (nmol/mg protein)

0.97 ± 0.03

0.86 ± 0.08

1.2 ± 008***

1.0 ± 0.07c

0.84 ± 0.06a

0.98 ± 0.05c

MPO (mu/mg protein)

16.92 ± 0.34

17.13 ± 0.31

24.65 ± 2.2***

18.88 ± 0.93b

19.69 ± 1.54c

16.93 ± 0.59c

CAT (u/mg protein)

146.79 ± 2.9

144.07 ± 2.03

84.89 ± 3.24***

127.9 ± 3.9***a

118.0 ± 3.64***a

134.4 ± 1.88*a

SOD (u/mg protein)

3.37 ± 0.02

3.37 ± 0.01

3.62 ± 0.05***

3.26 ± 0.08a

3.16 ± 0.09a

3.25 ± .0.06a

  1. Values are expressed as mean ± SEM of eight rats per group. Concentration is expressed as nmol/mg protein for MDA. Activity is expressed as unit/mg protein for CAT and SOD. Activity is expressed as m unit/mg protein for MPO. Significance was determined by one-way analysis of variance followed by Dennett's t test:* P < 0.05; ****P < 0.001 vs control. cP < 0.05; bP < 0.01; aP < 0.001 vs. CIS group.
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Theoretical Biology and Medical Modelling

ISSN: 1742-4682