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Figure 2 | Theoretical Biology and Medical Modelling

Figure 2

From: Modelling the correlation between EGFr expression and tumour cell radiosensitivity, and combined treatments of radiation and monoclonal antibody EGFr inhibitors

Figure 2

First phase to investigate the effects EGFr over-expression on radiosensitivity of Head and Neck cell lines. Data from literature[16, 18, 19] demonstrate the correlation between EGFr over-expression and reduced cellular radiosensitivity. This situation is indicated by an upward shift of the cell survival curve in the line over-expressing EGFr compared with normal EGFr expression. A polynomial regression allows radiosensitivity parameters corresponding to various surviving curves to be calculated.

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Theoretical Biology and Medical Modelling

ISSN: 1742-4682