Figure 5

Dose/fraction as a function of daily radiosensitivity for modulated fractionations with (a) same number of fractions as the reference schedule ( Example 3: 6 weeks ), (b) hypo-fractionation with one week less than the reference schedule ( Example 4: 5 weeks ) and hypo-fractionation with two weeks less than the reference schedule ( Example 5: 4 weeks ). The grey lines represent radiosensitivity corresponding to the pharmacokinetics curves of absorption for the EGFr mAb inhibitor. Abbreviations: (1) α/β = 5 Gy; (2) α/β = 9 Gy; (3) α/β = 12 Gy; (4) α/β = 14 Gy; (5) α/β = 15 Gy.