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Figure 3 | Theoretical Biology and Medical Modelling

Figure 3

From: Zinc finger arrays binding human papillomavirus types 16 and 18 genomic DNA: precursors of gene-therapeutics for in-situ reversal of associated cervical neoplasia

Figure 3

Schematics of zinc finger nucleases cleaving HPV type 16 genomic DNA. This figure offers a diagrammatic illustration of loci of action of zinc finger nucleases that target and cleave >18 bp (9x2 + 5, 6, or 7) sequences within the genomic DNA context of HPV type 16. Hits (blue, green, and gold bars) represent targets along the gene (red bars). ZFN hits in the graphic are color-coded on the basis of spacer size (5 bp = Blue; 6 bp = Green; 7 bp = Gold).

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Theoretical Biology and Medical Modelling

ISSN: 1742-4682