Figure 4From: Zinc finger arrays binding human papillomavirus types 16 and 18 genomic DNA: precursors of gene-therapeutics for in-situ reversal of associated cervical neoplasiaSchematics of zinc finger nucleases cleaving HPV type 18 genomic DNA. This figure offers a diagrammatic illustration of loci of action of zinc finger nucleases that target and cleave >18 bp (9x2 + 5, 6, or 7) sequences within the genomic DNA context of HPV type 18. Hits (blue, green, and gold bars) represent targets along the gene (red bars). ZFN hits in the graphic are color-coded on the basis of spacer size (5 bp = Blue; 6 bp = Green; 7 bp = Gold).Back to article page