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Table 3 Example of binary classification values

From: Animal models and conserved processes

  

Gold standard (human)

  

GS+

GS-

Test

T+

22

26

 

T-

22

30

Sensitivity = 22/(22 + 22) = 0.5

   

Specificity = 30/(26 + 30) = 0.54

   

Positive Predictive Value = 22/(22 + 26) = 0.46

   

Negative Predictive Value = 30/(22 + 30) = 0.58

   
  1. Binary classification values for cardiovascular toxicity test in monkeys from 25 compounds also tested in humans [48]. Note the values are approximately what would be expected from a coin toss.