Table 1 Gene sequences used in the analyses

EGFR

GI:998566 GI:998564

0.603

none

0.290

GI:229892268 GI:229892301 GI:229892299

0.212

none

Growth factor receptor

LNCaP

GI:429094 GI:429093 GI:429091

0.771

none

0.550

GI:19924155 GI:19924154

1.000

none

protease present in seminal plasma

HYAL1

GI:24497567 GI:24497563 GI:24497560

0.088

none

0.054

GI:386365498 GI:385648248 GI:385648249

0.751

none

candidate tumor suppressor

locus

ALDOA

GI:15488980 GI:15277570 GI:38197497

0.234

none

0.090

GI:342187210 GI:342187198 GI:342187192

0.331

none

glycolytic enzyme

PTPN3

GI:223941890 GI:223941884 GI:223941878

0.214

none

0.037

GI:223941893 GI:223941875

0.081

none

protein tyrosine phosphatase

NBL1

GI:323462168 GI:323276671 GI:323462166 GI:323462167

0.794

none

0.045

NC_000001.10 AC_000133.1

0.549

none

bone morphogenetic protein antagonist

BLCAP

GI:47939094 GI:28839694

0.385

none

0.033

GI:268370219 GI:268370215 GI:268370223 GI:268370217

0.077

none

tumour suppression gene

PRKA

GI:331284157 GI:116174749 GI:331284159

0.077

none

0.000

GI:331284154 GI:331284152 GI:331284159

0.497

none

regulates the effect of the cAMP-dependent protein kinase signaling pathway

STEAP2

GI:350276262 GI:350276256 GI:350276260

0.301

none

0.128

GI:100913195 GI:100913193 GI:100913197

0.484

none

metalloreductase

MAGED2

GI:41350319 GI:29171703 GI:29171704

0.899

none

0.015

NC_000023.10 AC_000155.1

0.034

diversifying

negative regulator of wild type p53 activity

FOLR1

GI:262331568 GI:262331573 GI:262331571 GI:262331569

0.470

none

0.007

NC_000011.9 AC_000143.1

1.000

none

folate receptor

EWSR1

GI:48734726 GI:38197249 GI:15029674 GI:13435962

0.310

none

0.072

GI:253970505 GI:253970501 GI:253970497 GI:253970503

0.171

none

involved gene expression, cell signaling, and RNA processing and transport

SHARPIN

GI:21706472 GI:19264111

0.451

none

0.003

GI:333805638 GI:118918414

0.290

none

Involved in NF-kappa-B activation and regulation of inflammation

NUDCD1

GI:13111833 GI:27694435 GI:21411491

0.806

none

0.005

GI:189571676 GI:189571678

0.071

none

tumor-associated antigen

PMEPA1

GI:51593770 GI:16198474 GI:22121998 GI:9255808

0.878

none

0.032

GI:40317615 GI:40317617 GI:40317619

0.353

none

Involved in down-regulation of the androgen receptor

CTAGE5

GI:313882513 GI:30411006 GI:39963693 GI:24659234

0.244

none

0.007

GI:134053863 GI:134053924 GI:134053890

0.002

purifying

tumor-associated antigen

IRAK3

GI:34785939 GI:46854383

0.791

none

0.003

GI:216547518 GI:216547503

1.000

none

receptor-associated kinase

PLS3

GI:34785158 GI:25058020 GI:288915540

0.255

none

0.015

GI:288915537 GI:288915538

0.243

none

actin-bundling protein

PRAME

GI:33874094 GI:25123208 GI:21328745

0.121

none

0.019

GI:46249372 GI:46249366 GI:46249370 GI:46249365

0.754

none

transcriptional repressor

TNFSF13

GI:33873809 GI:24934971 GI:211938417

0.211

none

0.162

GI:211938416 GI:310750386 GI:310750384

1.000

none

possibly involved in regulation of tumor cell growth and monocyte/macrophage-mediated immunological processes

ENOX2

GI:17939422 GI:80478559

0.070

none

0.006

GI:32528292 GI:32528290

1.000

none

growth-related cell surface protein

UQCC

GI:114108213 GI:77415336 GI:111598967 GI:296923772

0.452

none

0.008

GI:296923778 GI:296923775

1.000

none

enzyme involved in ubiquinol-cytochrome c reductase complex

ALOX15B

GI:85067502 GI:85067498 GI:39645887 GI:85067500

0.085

none

0.001

GI:182765463 GI:260166611

1.000

none

involved in the production of fatty acid hydroperoxides

TACSTD2

GI:166795235 GI:238914823 GI:14495610

0.340

none

0.014

NM_002353

AC_000133

1.000

none

cell surface receptor that transduces calcium signals

RAET1E

GI:149790140 GI:73909189

0.197

none

0.151

GI:21040248 GI:341915375 GI:343183384

0.586

none

delivers activating signals to NK cells

MAGEB1

GI:15489350 GI:164693182 GI:49456482

0.337

none

0.011

GI:284004909 GI:257796251 GI:257796250

0.0151

purifying

tumor-associated antigen

CSF1

GI:18088910 GI:166235151

0.413

none

0.142

GI:347360911 GI:166235149 GI:384475524

0.657

none

cytokine that controls the production, differentiation, and function of macrophages

CKAP2

GI:148664243 GI:148664200 GI:187950332 GI:15012012

0.278

none

0.084

NC_000013.10

AC_000145.1

0.320

none

involved in regulating aneuploidy, cell cycling, and cell death

MUC1

GI:182252 GI:115528448 GI:324120948

0.085

none

0.389

GI:324120957 GI:324120955 GI:324120951 GI:324120950

0.716

none

adhesion and anti-adhesion protein; involved in cell signaling

TMPRSS3

GI:14709533 GI:33991397 GI:145701031

0.736

none

0.008

GI:291167774 GI:145701029 GI:291167776

1.000

none

serine protease; plays a role in hearing

FOLR2

GI:34785969 GI:166064049 GI:166064051

0.090

none

0.005

GI:166064049 GI:166064053 GI:166064055

1.000

none

folate receptor

BYF3

GI:33873803 GI:110624585 GI:83641884 GI:83641883

0.137

none

0.049

GI:224177471 GI:1435190 GI:179571 GI:179575

0.686

none

involved in transcriptional initiation

TPBG

GI:33872201 GI:262205658 GI:262205664

0.807

none

0.012

NC_000006.11 AC_000138.1

0.521

none

possible cell adhesion molecule

EMP2

GI:16307197 GI:64692933

0.298

none

0.002

NC_000016.9 AC_000148.1

1.000

none

epithelial membrane protein

TGM6

GI:33331029 GI:33331031

1.00

none

0.000

NC_000020.10 AC_000152.1

0.266

none

associated with central nervous system development and motor function

NBR1

GI:112382227

GI:112382229

GI:112382228

0.359

none

0.504

GI:33869357 GI:111120332

0.018

purifying

Function unknown

CALM2

GI:19913528 GI:16924228 GI:14250064

0.04

diversifying

0.524

GI:229577210 GI:13097164

0.026

diversifying

Mediates enzymes, ion channels and other proteins

NRG1

GI:49522882 GI:34782767 GI:33873543

0.012

purifying

0.220

GI:236460384 GI:236464355

1

none

signaling protein that mediates cell-cell interactions

SYTL2

GI:244790015 GI:244790004 GI:244790009 GI:244790019

0.012

purifying

0.097

GI:82571721 GI:34784984 GI:21951814 GI:21984183

0.482

none

Involved in vesicle trafficking and melanosome distribution

BCAP31

GI:213511729 GI:213511011 GI:213511507 GI:40807164 GI:15680022

0.048

purifying

0.055

GI:374253795 GI:374253793

0.083

none

multi-pass endoplasmic reticulum transmembrane protein

ILK

GI:3150001 GI:16306740 GI: 8648884

0.013

purifying

0.007

GI:62420874 GI:62420871 GI:62420872 GI:8308037

0.222

none

serine/threonine protein kinase

LIMS1

GI:13529136 GI:336455030

0.016

purifying

0.007

GI:164697166 GI:34528462 GI:336455029

<0.001

purifying

likely involved in integrin signaling

CHST4

GI:23273964 GI:262205557 GI:262205902

0.016

purifying

0.021

GI:262205902 GI:262205557

0.018

purifying

sulfotransferase; modifies glycan structures on ligands of the lymphocyte homing receptor L-selectin

EBAG9

GI:17389375 GI:13528905 GI:18490914

0.009

purifying

0.072

GI37694064 GI:37694063 GI:158254733

0.289

none

tumor-associated antigen

NACA

GI:76779232 GI:333033786 GI:163965363

0.002

purifying

0.186

GI:85397251 GI:85397957 GI:60116922

0.755

none

Component of nascent polypeptide-associated complex; prevents mistranslocation of proteins

OCIAD1

GI:13097314 GI:56789926

0.036

purifying

0.065

GI:269914125 GI:269914123 GI:269914126 GI:269914124 GI:269954665

0.005

purifying

tumor-associated antigen