p
1
|
|
transition rate G1 → S
|
p
2
|
|
transition rate S → G2/M
|
p
3
|
|
transition rate G2/M → G1
|
p
4
|
|
apoptosis rate
|
p
5
|
|
influence factor of glucose
|
p
6
|
0.3
|
rate of glucose production
|
p
7
|
0.003
|
glucose effectiveness
|
| |
at zero insulin
|
p
8
|
|
insulin sensitivity
|
p
9
|
0.622
|
secretion rate of insulin
|
p
10
|
0.3
|
decay rate of insulin
|
p
11
|
0.0337
|
rate of provision increase
|
p
12
|
1.72×10−9 mg
|
average insulin amount per β‐cell
|
bv
|
3.33 ml
|
blood volume of 35g mouse
|
f
|
0.5
|
proportionality factor
|
h
|
5
|
Hill coefficient
|
P
0
|
186.506
|
Michaelis constant
|
|
1.65×10−3 mg
|
maximal amount of insulin
|
| |
per pancreas
|
k
|
3.3
|
Hill coefficient
|
C
|
149.78
|
Michaelis constant
|