Multiphysics model of a rat ventricular myocyte: A voltage-clamp study

Table 1 Q ₁₀ values used to model temperature variation

Parameter description	Q₁₀ value	References
Rate constants modulating I_Ca,L channel kinetics	2.4	[10, 11]
Maximum uptake rate of the SERCA pump	1.415	[12]
Maximum N a⁺ /C a⁺ exchange current (V_max)	1.77	[12]
Maximum plasma membrane C a^{2 +} -ATPase pump current ( ${\bar{I}}_{PMCA}$ )	4.3	[12]

Q₁₀ values in the electromechanical model were adopted from Rice et al. [13] with Qf_app, Qh_f, Qh_band Qg_xbdecreased to 2.25 to reproduce temperature dependence of peak force developed [14].

ISSN: 1742-4682