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Figure 13 | Theoretical Biology and Medical Modelling

Figure 13

From: The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model

Figure 13

Predicted death or recovery. Each dot represents one patient (who did not receive a liver transplant) and it is plotted so that the x coordinate is the dosage estimated by Remien et al.[10] and the y coordinate is the time since the dose estimated by Remien et al.[10]. Death or recovery is indicated by red or blue, respectively. We indicate the curve of hepatocyte depletion to 35% of normal (light grey), 30% of normal (medium grey), and 25% of normal (dark grey). If we use the 30% curve as the boundary between predicted death and predicted recovery, then we incorrectly predict only 3 deaths and 2 recoveries.

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