Skip to main content
Figure 4 | Theoretical Biology and Medical Modelling

Figure 4

From: Variable effect of co-infection on the HIV infectivity: Within-host dynamics and epidemiological significance

Figure 4

Correlation between the spVL and the increment on the VL in response to co-infection. We used different combination of the parameters k v and N, in which both parameters increase. The values used are reported in Table S1 in the Additional file 1. In A, the results suggest that viruses with low replicative capacity conducing to low spVL are generating limited increments on the VL. Conversely, viruses with potent replicative capacity that are able to produce elevated spVL would generate much larger increments on the VL. The pattern follows a logistic fit, which suggests a saturation effect at very high spVL. In B, the geometric per capita rate of growth was estimated for each spVL, and the pattern also shows a saturation fashion.

Back to article page