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Table 1 Model parameters

From: Periodicity of varicella-zoster virus in the presence of immune boosting and clinical reinfection with varicella

Parameter Notation Base value, refs. Range
Varicella transmission coefficient β 325 [27] 120–500
Rate of becoming infectious with varicella ω 26 [21] 20–32
the base value corresponds to the average latent period of ≈ 14 days    
Varicella recovery rate γ 50 [21] 40–60
the base value corresponds to the average infectious period of ≈ 7.3 days    
Loss of full immunity rate σ 0.10 [4,9,17] 0.0125–4.0
the base value corresponds to the average duration of “full” immunity of 10 years    
Varicella force of infection reduction coefficient for those ζ 0.10 [assumed] 0.0–1.0
who become reinfected following clearance of varicella    
Varicella force of infection reduction coefficient for those α 0.90 [assumed] 0.0–1.0
who become reinfected following HZ attack    
Boosting coefficient κ 3.0 [assumed] 0.0–20.0
Birth/death rate μ 0.0122 [29] 0.01–0.05
the base value corresponds to the average life expectancy of ≈ 82 years    
HZ reactivation rate η 0.05 [4,15,17] 0.0001–2.0
HZ recovery rate ρ 52 [17] 46–58
the base value corresponds to the average infectious period of ≈ 7 days    
Rate of HZ reactivation after loss of immunity following recovery from HZ δ 0.01 [12,23] 0.00–0.10
Rate of loss of immunity to VZV after recovery from HZ θ 4.0 [assumed] 0.00–12.0
the base value corresponds to immunity lasting 3 months on average    
Relative VZV infectiousness of HZ p 0.001 [10,17] 0.00–0.10
  1. All rates in this table are per year. Note that β and p are used to define the force of infection (2).