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Table 3 Summary of the equations used for the numerical simulation depicted in Figs. 2 and 3

From: Proposal of a hybrid approach for tumor progression and tumor-induced angiogenesis

Variable

Equation

Proliferative tumor cells density

P t +·(vP)=Γ P+f QP Q−(f PQ +f PN )P

Quiescent cells density

Q t +·(vQ)=f PQ P−(f QP +f QN )Q

Necrotic tumor cells density

N t +·(vN)=f PN P+f QN Q

Host cells density

S t +·(vS)=0

Endothelial cells density

ρ t +·(vρ)+·(g CH )=f ρ ρ ρ

[O 2]

C t ·(D C C)=−g C +h C

[V E G F]

α t ·(D α α)=−g α +h α

Advection velocity

v=−kφ

Pressure

·(kφ)=Γ P+f ρ ρ ρ·(g CH )