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Table 4 Results of PDON-driven search in response to expert competency questions. In contrast to PubMed queries, PDON-driven search in SCAIView generated a list of entities that precisely answer the competency questions

From: PDON: Parkinson’s disease ontology for representation and modeling of the Parkinson’s disease knowledge domain

Competency question

Entities

PubMed ID

Return all literature references mentioning drugs used to treat 'freezing' in PD.

Levodopa

6858781, 16222436, 12217618, 15262734

Selegiline

12112107, 22324564, 18937611

Amantadine

23185280, 24057149

Atomoxetine

19361809

L-threo-DOPS

6337612, 8174332

Droxidopa

23242741, 7834960

Manganese

8351000

Galantamanie

23130517, 18427456

Methylphenidate

23076544

Deprenyl

11425939

Rasagiline

21389939

Return literature references containing genes that provide resistance to PD in the animal model MPTP.

Nos1

12490535, 8643444

Nos2

10581083

Sod1

1578260

Ccl2

17258864

Mcpt1

17258864