Fig. 5
From: Bioelectric memory: modeling resting potential bistability in amphibian embryos and mammalian cells
Examples of simulations not exhibiting bistability. We examined instances of models generating non-bistable behavior in the X + Y + leak amphibian case (10:10:1 maximal conductance ratio). Simulations were initialized at 30 voltages ranging from −140 to 150 mV and clamped for 50 ms before release. a The Kv1.2 + Kir2.1 + leak model exhibits a hyperpolarization-evoked transient caused by clamping at –140 mV. b The Cav2.2 + Kv2.2 + leak model does not appear to be asymptotically stable