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Fig. 2 | Theoretical Biology and Medical Modelling

Fig. 2

From: A Boolean network model of human gonadal sex determination

Fig. 2

Fixed point attractors of the Boolean model of gonadal sex determination. The attractors were obtained by simulating all possible (219) initial activation states. The attractor with the largest basin of attraction (50.95 %) can be interpreted as the gene expression profile observed in the somatic pre-Granulosa cells. The attractor with the second-largest basin (48.91 %) can be interpreted as the gene expression profile observed in the somatic pre-Sertoli cells. The model also presents a third attractor with a small basin covering only 0.14 % of the state space interpreted as a null attractor due to a UGR node set to zero

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