Table 3 Summary of model parameter values, description of the resultant pathophysiology, with associated descriptor
Name and value | Pathophysiology or function | Descriptor |
|---|---|---|
β=0.8 | Low normal insulin-dependent | Mild IR |
glucose utilization | ||
β=0.6 | Low normal insulin-dependent | Severe IR |
glucose utilization decreased by 25 % | ||
α=0.8 | Low normal insulin secretion | Mild I D p |
α=0.6 | Low normal insulin secretion | Severe I D p |
decreased by 25 % | ||
d i =0.17 | High normal IC | Borderline IC |
d i =0.25 | High normal IC increased by 50 % | I C 50 |
\(\digamma = 2\) | Normal gluconeogenesis rate doubled | No descriptor |